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Article

Characterization of naturally occurring and recombinant human N-acetyltransferase variants encoded by NAT1.

Molecular pharmacology - 1 Aug 2000

de León J H, Vatsis K P, Weber W W

Abstract excerpt

The genotype at the NAT1* locus of an interethnic population of 38 unrelated subjects was determined by direct sequencing of 1.6-kb fragments amplified by PCR. The coding exon alone and together with the 3' noncoding exon of the wild-type (NAT1*4) and the three mutant alleles (NAT1*10, *11, and *16) detected was expressed in Escherichia coli and COS-1 cells, respectively, and the cytosolic fraction of mononuclear...

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Identifiers

PMID: 10908296
DOI: 10.1124/mol.58.2.288

Genes

NAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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