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Article

β-AR polymorphisms and glycemic and lipid parameters in hypertensive individuals receiving carvedilol or metoprolol.

American journal of hypertension - 1 Aug 2012

Vardeny Orly, Nicholas Gabriel, Andrei Alina, Buhr Kevin A, Hermanson Matt P, Moran John J, Detry Michelle A, Stein James H

Abstract excerpt

BACKGROUND: β-Blocker therapy and β-adrenergic receptor (β-AR) polymorphisms are associated with increases in glucose and lipid levels. We investigated associations of common β1 and β2-AR single-nucleotide polymorphisms (SNPs) with metabolic and lipid variables, and examined interactions with β-blocker treatment assignment to affect these parameters. METHODS: This was a post hoc analysis of a double-blinded...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22647787
DOI: 10.1038/ajh.2012.54
PMCID: PMC4126246

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