Article
Molecular characterization of caveolin-1 in pigs infected with Haemophilus parasuis.
Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2011
Liu Xiang-Dong, Chen Hong-Bo, Tong Qin, Li Xin-Yun, Zhu Meng-Jin, Wu Zhen-Fang, Zhou Rui, Zhao Shu-Hong
Abstract excerpt
Caveolin-1 (Cav1) plays a critical role in the invasion of pathogenic microbes into host cells, yet little is known about porcine Cav1. In this study, we provide the molecular characterization of Cav1 in pigs following stimulation with LPS/polyinosinic-polycytidylic acid as well as during infection with Haemophilus parasuis. The porcine Cav1 gene is 35 kb long and is located at SSC18q21; two isoforms (Cav1-α and...
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