Genome-wide association study of disease resilience traits from a natural polymicrobial disease challenge model in pigs identifies the importance of the major histocompatibility complex region.

Abstract excerpt

Infectious diseases cause tremendous financial losses in the pork industry, emphasizing the importance of disease resilience, which is the ability of an animal to maintain performance under disease. Previously, a natural polymicrobial disease challenge model was established, in which pigs were challenged in the late nursery phase by multiple pathogens to maximize expression of genetic differences in disease...

Topics

• Animals
• Disease Models, Animal
• Genome
• Genome-Wide Association Study
• Major Histocompatibility Complex
• Phenotype
• Polymorphism, Single Nucleotide
• Quantitative Trait Loci
• Swine