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Article

Specific functions of Drosophila amyloid precursor-like protein in the development of nervous system and nonneural tissues.

Journal of neurobiology - 1 Dec 2004

Li Yan, Liu Tong, Peng Yueqing, Yuan Chunyan, Guo Aike

Abstract excerpt

Drosophila amyloid precursor-like protein (APPL) is expressed extensively in the nervous system soon after neuronal differentiation. By utilizing different transgenic flies, we studied the physiological function of two APPL protein forms, membrane-bound form (mAPPL) and secreted form (sAPPL), in neural development. We found that neither deletion nor overexpression of APPL protein altered the gross structure of...

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Identifiers

PMID: 15389603
DOI: 10.1002/neu.20048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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