Article
Investigating synapse formation and function using human pluripotent stem cell-derived neurons.
Proceedings of the National Academy of Sciences of the United States of America - 15 Feb 2011
Kim Ji-Eun, O'Sullivan Matthew L, Sanchez Christopher A, Hwang Minju, Israel Mason A, Brennand Kristen, Deerinck Thomas J, Goldstein Lawrence S B, Gage Fred H, Ellisman Mark H, Ghosh Anirvan
Abstract excerpt
A major goal of stem-cell research is to identify conditions that reliably regulate their differentiation into specific cell types. This goal is particularly important for human stem cells if they are to be used for in vivo transplantation or as a platform for drug development. Here we describe the establishment of procedures to direct the differentiation of human embryonic stem cells and human induced...
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