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Article

Microscopic and early-stage ovarian cancers in BRCA1/2 mutation carriers: building a model for early BRCA-associated tumorigenesis.

Cancer prevention research (Philadelphia, Pa.) - 1 Mar 2011

Yates Melinda S, Meyer Larissa A, Deavers Michael T, Daniels Molly S, Keeler Elizabeth R, Mok Samuel C, Gershenson David M, Lu Karen H

Abstract excerpt

Risk-reducing salpingo-oophorectomy (RRSO) is the cornerstone of ovarian cancer prevention in BRCA1/2 mutation carriers. Occult fallopian tube and ovarian cancers have been reported in a small percentage of BRCA1/2 mutation carriers undergoing RRSO. Here, we review our single-institution experience with RRSO in BRCA1/2 mutation carriers to characterize cases of microscopic cancers in these patients. At the time...

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Share to Disease Progression
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genes, BRCA1

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Share to Germ-Line Mutation

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Source

Open in PubMed Open full text

Identifiers

PMID: 21278312
DOI: 10.1158/1940-6207.CAPR-10-0266
PMCID: PMC3048908

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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