Pathologic findings and clinical outcomes in women undergoing risk-reducing surgery to prevent ovarian and fallopian tube carcinoma: A large prospective single institution experience.

doi:10.1016/j.ygyno.2020.02.006

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Article

Pathologic findings and clinical outcomes in women undergoing risk-reducing surgery to prevent ovarian and fallopian tube carcinoma: A large prospective single institution experience.

Gynecologic oncology - 1 May 2020

Rush Shannon K, Swisher Elizabeth M, Garcia Rochelle L, Pennington Kathryn P, Agnew Kathy J, Kilgore Mark R, Norquist Barbara M

Abstract excerpt

OBJECTIVES: Risk-reducing salpingo-oophorectomy (RRSO) is recommended for women at increased risk of ovarian, fallopian tube (FT), and peritoneal carcinoma (collectively OC). We describe rates of occult neoplasia in the largest single-institution prospective cohort of women undergoing RRSO, including those with mutations in non-BRCA homologous repair (HRR) genes. METHODS: Participants undergoing RRSO enrolled in...

Topics

Adult
Aged
BRCA2 Protein
Cohort Studies
Fallopian Tube Neoplasms
Fallopian Tubes
Fanconi Anemia Complementation Group N Protein
Female
Genetic Predisposition to Disease
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Mutation

Neoplasms, Unknown Primary

Ovarian Neoplasms

Ovary

Pedigree

Prospective Studies

Salpingo-oophorectomy

Source

Open in PubMed

Identifiers

PMID: 32199636
DOI: 10.1016/j.ygyno.2020.02.006

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