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Article

When pigs fly: immunomagnetic separation facilitates rapid determination of Pig-a mutant frequency by flow cytometric analysis.

Mutation research - 3 Apr 2011

Dertinger Stephen D, Bryce Steven M, Phonethepswath Souk, Avlasevich Svetlana L

Abstract excerpt

In vivo mutation assays based on the Pig-a null phenotype, that is, the absence of cell surface glycosylphosphatidylinositol (GPI) anchored proteins such as CD59, have been described. This work has been accomplished with hematopoietic cells, most often rat peripheral blood erythrocytes (RBCs) and reticulocytes (RETs). The current report describes new sample processing procedures that dramatically increase the...

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Source

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Identifiers

PMID: 21277384
DOI: 10.1016/j.mrgentox.2011.01.009
PMCID: PMC3064711

Genes

RET
GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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When pigs fly: immunomagnetic separation facilitates rapid determination of Pig-a mutant frequency by flow cytometric analysis.PMID 21277384Read ↗

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