Article
-137 (G/C) IL-18 promoter polymorphism in patients with inflammatory bowel disease.
Scandinavian journal of gastroenterology - 1 Dec 2005
Haas Stephan L, Andreas Koch W, Schreiber Stefan, Reinhard Iris, Koyama Noriko, Singer Manfred V, Böcker Ulrich
Abstract excerpt
OBJECTIVE: There is strong evidence that genetic factors contribute to the susceptibility for inflammatory bowel diseases (IBD). Recently, IL-18 promoter polymorphisms were characterized as risk factors for inflammatory diseases such as sepsis, asthma and adult-onset Still's disease. The aim of this study was to determine whether the -137 (G/C) IL-18 promoter polymorphism was associated with IBD susceptibility....
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