Article
Immunohistochemical localization of receptor for advanced glycation end (RAGE) products in the R6/2 mouse model of Huntington's disease.
Brain research bulletin - 10 Feb 2012
Anzilotti Serenella, Giampà Carmela, Laurenti Daunia, Perrone Lorena, Bernardi Giorgio, Melone Mariarosa A B, Fusco Francesca R
Abstract excerpt
The receptor for advanced glycation end (RAGE) products is a multi-ligand receptor that belongs to the immunoglobulin superfamily of cell surface receptors, whose ligands are known to be upregulated in neuropathological conditions. RAGE upregulation has been described in neurodegenerative diseases, such as Alzheimer's disease, Creutzfeldt-Jakob's disease and Huntington's disease (HD). To analyze in detail the...
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