Article
Methylenetetrahydrofolate reductase variants associated with hypertension and cardiovascular disease interact with dietary polyunsaturated fatty acids to modulate plasma homocysteine in puerto rican adults.
The Journal of nutrition - 1 Apr 2011
Huang Tao, Tucker Katherine L, Lee Yu-Chi, Crott Jimmy W, Parnell Laurence D, Shen Jian, Smith Caren E, Ordovas Jose M, Li Duo, Lai Chao-Qiang
Abstract excerpt
Although methylenetetrahydrofolate reductase (MTHFR) genetic variants are associated with plasma homocysteine (Hcy) and cardiovascular disease (CVD), little is known whether dietary fatty acid intake modulates these associations. The goal was to examine the interaction of MTHFR variants with dietary fatty acids influencing plasma Hcy in 995 Boston Puerto Rican adults. We found that plasma Hcy concentration was...
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