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Article

Establishment of a TGFβ-Induced Post-Transcriptional EMT Gene Signature

20 Dec 2012

Abstract excerpt

A major challenge in the clinical management of human cancers is to accurately stratify patients according to risk and likelihood of a favorable response. Stratification is confounded by significant phenotypic heterogeneity in some tumor types, often without obvious criteria for subdivision. Despite intensive transcriptional array analyses, the identity and validation of cancer specific 'signature genes' remains...

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PMID: 23285117
DOI: 10.1371/journal.pone.0052624

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