Article
Giant panda genomic data provide insight into the birth-and-death process of mammalian major histocompatibility complex class II genes.
PloS one - 1 Jan 2009
Wan Qiu-Hong, Zeng Chang-Jun, Ni Xiao-Wei, Pan Hui-Juan, Fang Sheng-Guo
Abstract excerpt
To gain an understanding of the genomic structure and evolutionary history of the giant panda major histocompatibility complex (MHC) genes, we determined a 636,503-bp nucleotide sequence spanning the MHC class II region. Analysis revealed that the MHC class II region from this rare species contained 26 loci (17 predicted to be expressed), of which 10 are classical class II genes (1 DRA, 2 DRB, 2 DQA, 3 DQB, 1...
Topics
- Animals
- Base Sequence
- Cats
- Cattle
- Dogs
- Evolution, Molecular
- Genetic Variation
- Genome
- Histocompatibility Antigens Class II
- Humans
- Mammals
- Mice
- Models, Genetic
- Phylogeny
- Ursidae