Article
Recombinant DNA methods in hemophilia A: carrier detection and prenatal diagnosis.
Seminars in thrombosis and hemostasis - 1 Oct 1990
Sadler J E
Abstract excerpt
Hemophilia A is a serious inherited bleeding disorder of man that is caused by deficiency of blood coagulation Factor VIII. Major clinical problems in the treatment of hemophilia A include the transmission of disease by therapeutic blood products and the development of alloantibody inhibitors to transfused Factor VIII. The genetic counseling of affected families is made more difficult by the inherent inaccuracy...
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