Article
Detection of carriers of haemophilia A: use of bioassays and restriction fragment length polymorphisms (RFLP).
Australian and New Zealand journal of medicine - 1 Apr 1996
Rudzki Z, Rodgers S E, Sheffield L J, Lloyd J V
Abstract excerpt
BACKGROUND: Haemophilia A is a sex-linked bleeding disorder carried by unaffected females. Currently, the two main methods used for the determination of carrier status in women from families with haemophilia A are bioassays and DNA-based assays using restriction fragment length polymorphisms (RFLP). AIM: The aim of this paper was to assess the current usefulness of these two methods. METHODS: Bioassays measured...
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