Article
Honduras HIV cohort: HLA class I and CCR5-Δ32 profiles and their associations with HIV disease outcome.
Microbiology spectrum - 12 Dec 2023
Valenzuela-Ponce Humberto, Carbajal Candy, Soto-Nava Maribel, Tapia-Trejo Daniela, García-Morales Claudia, Murillo Wendy, Lorenzana Ivette, Reyes-Terán Gustavo, Ávila-Ríos Santiago
Abstract excerpt
IMPORTANCE: We identify both canonical and novel human leukocyte antigen (HLA)-HIV associations, providing a first step toward improved understanding of HIV immune control among the understudied Honduras Mestizo population. Our results are relevant to understanding the protective or detrimental effects of HLA subtypes in Latin America because their unique HLA diversity poses challenges for designing vaccines...
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