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Article

Maintenance of immune hyporesponsiveness to melanosomal proteins by DHICA-mediated antioxidation: Possible implications for autoimmune vitiligo.

Free radical biology & medicine - 1 May 2011

Liu Xiao-Ming, Zhou Qiong, Xu Shi-Zheng, Wakamatsu Kazumasa, Lei Tie-Chi

Abstract excerpt

Melanocyte destruction in the skin of vitiligo patients has been considered to be a consequence of an autoimmune response against melanosomal proteins. However, little is known about the molecular mechanisms by which the immune system recognizes these sequestered intracellular self-proteins, which are confined in specialized organelles termed melanosomes, and is provoked into an autoimmune response to...

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Identifiers

PMID: 21256957
DOI: 10.1016/j.freeradbiomed.2011.01.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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