Article
Vitiligo: a possible model of degenerative diseases.
PloS one - 1 Jan 2013
Bellei Barbara, Pitisci Angela, Ottaviani Monica, Ludovici Matteo, Cota Carlo, Luzi Fabiola, Dell'Anna Maria Lucia, Picardo Mauro
Abstract excerpt
Vitiligo is characterized by the progressive disappearance of pigment cells from skin and hair follicle. Several in vitro and in vivo studies show evidence of an altered redox status, suggesting that loss of cellular redox equilibrium might be the pathogenic mechanism in vitiligo. However, despite the numerous data supporting a pathogenic role of oxidative stress, there is still no consensus explanation...
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