Article
Vitiligo: interplay between oxidative stress and immune system.
Experimental dermatology - 1 Apr 2013
Laddha Naresh C, Dwivedi Mitesh, Mansuri Mohmmad S, Gani Amina R, Ansarullah Md, Ramachandran A V, Dalai Sarat, Begum Rasheedunnisa
Abstract excerpt
Vitiligo is a multifactorial polygenic disorder with a complex pathogenesis, linked with both genetic and non-genetic factors. The precise modus operandi for vitiligo pathogenesis has remained elusive. Theories regarding loss of melanocytes are based on autoimmune, cytotoxic, oxidant-antioxidant and neural mechanisms. Reactive oxygen species (ROS) in excess have been documented in active vitiligo skin. Numerous...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.