Article
Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism.
Journal of the American College of Cardiology - 21 Aug 2012
Helgadottir Anna, Gretarsdottir Solveig, Thorleifsson Gudmar, Holm Hilma, Patel Riyaz S, Gudnason Thorarinn, Jones Gregory T, van Rij Andre M, Eapen Danny J, Baas Annette F, Tregouet David-Alexandre, Morange Pierre-Emmanuel, Emmerich Joseph, Lindblad Bengt, Gottsäter Anders, Kiemeny Lambertus A, Lindholt Jes S, Sakalihasan Natzi, Ferrell Robert E, Carey David J, Elmore James R, Tsao Philip S, Grarup Niels, Jørgensen Torben, Witte Daniel R, Hansen Torben, Pedersen Oluf, Pola Roberto, Gaetani Eleonora, Magnadottir Hulda B, Wijmenga Cisca, Tromp Gerard, Ronkainen Antti, Ruigrok Ynte M, Blankensteijn Jan D, Mueller Thomas, Wells Philip S, Corral Javier, Soria Jose Manuel, Souto Juan Carlos, Peden John F, Jalilzadeh Shapour, Mayosi Bongani M, Keavney Bernard, Strawbridge Rona J, Sabater-Lleal Maria, Gertow Karl, Baldassarre Damiano, Nyyssönen Kristiina, Rauramaa Rainer, Smit Andries J, Mannarino Elmo, Giral Philippe, Tremoli Elena, de Faire Ulf, Humphries Steve E, Hamsten Anders, Haraldsdottir Vilhelmina, Olafsson Isleifur, Magnusson Magnus K, Samani Nilesh J, Levey Allan I, Markus Hugh S, Kostulas Konstantinos, Dichgans Martin, Berger Klaus, Kuhlenbäumer Gregor, Ringelstein E Bernd, Stoll Monika, Seedorf Udo, Rothwell Peter M, Powell Janet T, Kuivaniemi Helena, Onundarson Pall T, Valdimarsson Einar, Matthiasson Stefan E, Gudbjartsson Daniel F, Thorgeirsson Guðmundur, Quyyumi Arshed A, Watkins Hugh, Farrall Martin, Thorsteinsdottir Unnur, Stefansson Kari
Abstract excerpt
OBJECTIVES: The purpose of this study is investigate the effects of variants in the apolipoprotein(a) gene (LPA) on vascular diseases with different atherosclerotic and thrombotic components. BACKGROUND: It is unclear whether the LPA variants rs10455872 and , which correlate with lipoprotein(a) levels and coronary artery disease (CAD), confer susceptibility predominantly via atherosclerosis or...