Article
An image-based 384-well high-throughput screening method for the discovery of biofilm inhibitors in Vibrio cholerae.
Molecular bioSystems - 1 Apr 2011
Peach Kelly C, Bray Walter M, Shikuma Nicholas J, Gassner Nadine C, Lokey R Scott, Yildiz Fitnat H, Linington Roger G
Abstract excerpt
Bacterial biofilms are assemblages of bacterial cells and extracellular matrix that result in the creation of surface-associated macrocolony formation. Most bacteria are capable of forming biofilms under suitable conditions. Biofilm formation by pathogenic bacteria on medical implant devices has been linked to implant rejection in up to 10% of cases, due to biofilm-related secondary infections. In addition,...
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