Article

The Development of a Pipeline for the Identification and Validation of Small-Molecule RelA Inhibitors for Use as Anti-biofilm Drugs

2020-07-29

Abstract excerpt

Biofilm infections have no effective medical treatments and can only be disrupted via physical means. This means that any biofilm infection that is not addressable surgically can never be eliminated and can only be managed as a chronic disease. Therefore, there is an urgent need for the development of new classes of drugs that can target the metabolic mechanisms within biofilms which render them recalcitrant to tr...

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Literature Corpus work: 2d367c1d-db67-53fe-9f36-a31229514aff
DOI: 10.1101/2020.07.27.224345

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