Comparative evaluation of small molecules reported to be inhibitors of Staphylococcus aureus biofilm formation

Abstract excerpt

ABSTRACT Biofilm formation is an important characteristic of many Staphylococcus aureus infections because it limits the efficacy of host defenses and conventional antibiotic therapy. There are many literature reports that describe small molecule inhibitors of S. aureus biofilm formation, but the lack of direct comparisons and differences in the methods used to assess inhibition make it impossible to assess the...

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