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Article

tRNA accumulation and suppression of the bldA phenotype during development in Streptomyces coelicolor.

Molecular microbiology - 1 Mar 2011

Pettersson B M Fredrik, Kirsebom Leif A

Abstract excerpt

Streptomyces coelicolor undergoes distinct morphological changes as it grows on solid media where spores differentiate into vegetative and aerial mycelium that is followed by the production of spores. Deletion of bldA, encoding the rare tRNA(Leu) UAA, blocks development at the stage of vegetative mycelium formation. From previous data it appears that tRNA(Leu) UAA accumulates relatively late during growth while...

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Identifiers

PMID: 21244529
DOI: 10.1111/j.1365-2958.2011.07543.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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tRNA accumulation and suppression of the bldA phenotype during development in Streptomyces coelicolor.PMID 21244529Read ↗

The bldA-encoded tRNA is poorly expressed in the bldI mutant of Streptomyces coelicolor A3(2).Semantic proximity Read ↗

The Gene bldA, a regulator of morphological differentiation and antibiotic production in streptomyces.Semantic proximity Read ↗

Developmentally regulated cleavage of tRNAs in the bacterium Streptomyces coelicolor.Semantic proximity Read ↗

The level of a transcript required for production of a Streptomyces coelicolor antibiotic is conditionally dependent on a tRNA gene.Semantic proximity Read ↗

Small non-coding RNAs in Streptomyces coelicolorSemantic proximity Read ↗

The effects of a unique D-loop structure of a minor tRNA(UUALeu) from Streptomyces on its structural stability and amino acid accepting activity.Semantic proximity Read ↗

A rare leucine codon in adpA is implicated in the morphological defect of bldA mutants of Streptomyces coelicolor.Semantic proximity Read ↗

Colonial differentiation in Streptomyces coelicolor depends on translation of a specific codon within the adpA gene.Semantic proximity Read ↗

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The endonuclease activity of RNase III is required for the regulation of antibiotic production by Streptomyces coelicolor.Semantic proximity Read ↗

The positive activator of cephamycin C and clavulanic acid production in Streptomyces clavuligerus is mistranslated in a bldA mutant.Semantic proximity Read ↗

Expression of the regulatory protein LndI for landomycin E production in Streptomyces globisporus 1912 is controlled by the availability of tRNA for the rare UUA codon.Semantic proximity Read ↗

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