Article
The SmpB-tmRNA tagging system plays important roles in Streptomyces coelicolor growth and development.
PloS one - 1 Jan 2009
Yang Chunzhong, Glover John R
Abstract excerpt
The ssrA gene encodes tmRNA that, together with a specialized tmRNA-binding protein, SmpB, forms part of a ribonucleoprotein complex, provides a template for the resumption of translation elongation, subsequent termination and recycling of stalled ribosomes. In addition, the mRNA-like domain of tmRNA encodes a peptide that tags polypeptides derived from stalled ribosomes for degradation. Streptomyces are unique...
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