Article
A rare leucine codon in adpA is implicated in the morphological defect of bldA mutants of Streptomyces coelicolor.
Molecular microbiology - 1 Oct 2003
Takano E, Tao M, Long F, Bibb Maureen J, Wang L, Li W, Buttner M J, Bibb Mervyn J, Deng Z X, Chater K F
Abstract excerpt
Streptomycetes are mycelial bacteria that produce sporulating aerial hyphae on solid media. Bald (bld) mutants fail to form aerial mycelium under at least some conditions. bldA encodes the only tRNA species able to read the leucine codon UUA efficiently, implying the involvement of a TTA-containing gene in initiating aerial growth. One candidate for such a gene was bldH, because the bldH109 mutant of Streptomyces...
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