Article
The effects of a unique D-loop structure of a minor tRNA(UUALeu) from Streptomyces on its structural stability and amino acid accepting activity.
Nucleic acids research - 11 Aug 1992
Ueda Y, Kumagai I, Miura K
Abstract excerpt
Streptomyces bldA gene, which encodes a tRNA corresponding to a very minor leucine codon, UUA, regulates pleiotropic gene expression which is involved in sporulation and secondary metabolism. The unique structural feature of this tRNA is the lack of GG sequence in dihydrouridine loop (D-loop) that generally is conserved in tRNAs involved in cytoplasmic protein biosynthesis. In order to investigate the...
Topics
- Base Sequence
- Cloning, Molecular
- Electrophoresis
- Escherichia coli
- Kinetics
- Leucine
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Plasmids
- RNA, Bacterial