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Article

Characterization of the terminal activation step catalyzed by oxygenase CmmOIV of the chromomycin biosynthetic pathway from Streptomyces griseus.

Biochemistry - 1 Mar 2011

Bosserman Mary A, Flórez Ana B, Shaaban Khaled A, Braña Alfredo F, Salas Jose A, Méndez Carmen, Rohr Jürgen

Abstract excerpt

Inactivation and initial interrogation of key oxygenase CmmOIV of the biosynthetic pathway of chromomycin A(3) in Streptomyces griseus ssp. griseus revealed that a completely methylated and acetylated prechromomycin is the preferred substrate of this enzyme. This suggests that the three sugar dec...

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PMID: 21244022
DOI: 10.1021/bi1016205
PMCID: PMC3043137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21244022-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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