Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of starter unit availability on the spectrum of manumycin-type metabolites produced by Streptomyces nodosus ssp. asukaensis.

Journal of applied microbiology - 1 Nov 2011

Pospíšil S, Petříčková K, Sedmera P, Halada P, Olšovská J, Petříček M

Abstract excerpt

AIMS: Production of minor asukamycin congeners and its new derivatives by combination of targeted genetic manipulations with specific precursor feeding in the producer of asukamycin, Streptomyces nodosus ssp. asukaensis. METHODS AND RESULTS: Structural variations of manumycins lie only in the diverse initiation of the 'upper' polyketide chain. Inactivation of the gene involved in the biosynthesis of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acyl Coenzyme A
Share to Amino Acids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Culture Media

Share to Genetic Engineering

Share to Mutagenesis, Insertional

Share to Polyenes

Share to Polyunsaturated Alkamides

Share to Streptomyces

Source

Identifiers

PMID: 21854515
DOI: 10.1111/j.1365-2672.2011.05132.x

Genes

IMPACT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of starter unit availability on the spectrum of manumycin-type metabolites produced by Streptomyces nodosus ssp. asukaensis.PMID 21854515Read ↗

Complete Characterization of the Seventeen Step Moenomycin Biosynthetic PathwaySemantic proximity Read ↗

Discovery and Biosynthesis of Nyuzenamides D and E by Genome Mining in Streptomyces hygroscopicusSemantic proximity Read ↗

Superior production of heavy pamamycin derivatives using a bkdR deletion mutant of Streptomyces albus J1074/R2.Semantic proximity Read ↗

Oxazolomycin Biosynthesis in Streptomyces albus JA3453 Featuring an “Acyltransferase-less” Type I Polyketide Synthase That Incorporates Two Distinct Extender UnitsSemantic proximity Read ↗

Nitrogen incorporation in the biosynthetic pathway of the nitrogen-containing polyketide, pamamycin in Streptomyces alboniger.Semantic proximity Read ↗

Biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces nourseiSemantic proximity Read ↗

[Genes for biosynthesis of butenolide-like signalling molecules in Streptomyces ghanaensis, their role in moenomycin production].Semantic proximity Read ↗

Systems metabolic engineering of the primary and secondary metabolism of Streptomyces albidoflavus enhances production of the reverse antibiotic nybomycin against multi-resistant Staphylococcus aureusSemantic proximity Read ↗

Improving the N-terminal diversity of sansanmycin through mutasynthesis.Semantic proximity Read ↗

Combined use of design of experiments and metabolic engineering for optimization of nogalamycin productionSemantic proximity Read ↗

Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway.Semantic proximity Read ↗

Characterization of Streptomyces MITKK-103, a newly isolated actinomycin X2-producerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.