Disease characterization using LQTS-specific induced pluripotent stem cells.

doi:10.1093/cvr/cvs206

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Article

Disease characterization using LQTS-specific induced pluripotent stem cells.

Cardiovascular research - 1 Sept 2012

Egashira Toru, Yuasa Shinsuke, Suzuki Tomoyuki, Aizawa Yoshiyasu, Yamakawa Hiroyuki, Matsuhashi Tomohiro, Ohno Yohei, Tohyama Shugo, Okata Shinichiro, Seki Tomohisa, Kuroda Yusuke, Yae Kojiro, Hashimoto Hisayuki, Tanaka Tomofumi, Hattori Fumiyuki, Sato Toshiaki, Miyoshi Shunichiro, Takatsuki Seiji, Murata Mitsushige, Kurokawa Junko, Furukawa Tetsushi, Makita Naomasa, Aiba Takeshi, Shimizu Wataru, Horie Minoru, Kamiya Kaichiro, Kodama Itsuo, Ogawa Satoshi, Fukuda Keiichi

Abstract excerpt

AIMS: Long QT syndrome (LQTS) is an inheritable and life-threatening disease; however, it is often difficult to determine disease characteristics in sporadic cases with novel mutations, and more precise analysis is necessary for the successful development of evidence-based clinical therapies. This study thus sought to better characterize ion channel cardiac disorders using induced pluripotent stem cells (iPSCs)....

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PMID: 22739119
DOI: 10.1093/cvr/cvs206

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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