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Article

Common variants of IRF3 conferring risk of schizophrenia.

Journal of psychiatric research - 1 May 2015

Li Xiao, Zhang Wen, Lencz Todd, Darvasi Ariel, Alkelai Anna, Lerer Bernard, Jiang Hong-Yan, Zhang Deng-feng, Yu Li, Xu Xiu-Feng, Li Ming, Yao Yong-Gang

Abstract excerpt

Schizophrenia is a brain disorder with high heritability. Recent studies have implicated genes involved in the immune response pathway in the pathogenesis of schizophrenia. Interferon regulatory factor 3 (IRF3), a virus-immune-related gene, activates the transcription of several interferon-induced genes, and functionally interacts with several schizophrenia susceptibility genes. To test whether IRF3 is a...

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PMID: 25843157
DOI: 10.1016/j.jpsychires.2015.03.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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