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Article

Multiple HIV-1 infections with evidence of recombination in heterosexual partnerships in a low risk Rural Clinical Cohort in Uganda.

Virology - 1 Mar 2011

Ssemwanga Deogratius, Lyagoba Frederick, Ndembi Nicaise, Mayanja Billy N, Larke Natasha, Wang Shuyi, Baalwa Joshua, Williamson Carolyn, Grosskurth Heiner, Kaleebu Pontiano

Abstract excerpt

We report on the frequency of multiple infections, generation of recombinants and consequences on disease progression in 35 HIV-1 infected individuals from 7 monogamous and 6 polygamous partnerships within a Rural Clinical Cohort in Uganda. The env-C2V3, gag-p24 and pol-IN genes were sequenced. Single genome amplified half genome sequences were used to map recombination breakpoints. Three participants were dually...

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Identifiers

PMID: 21239033
DOI: 10.1016/j.virol.2010.12.025
PMCID: PMC3041926

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