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Article

A WNK4 gene variant relates to osteoporosis and not to hypertension in the Portuguese population.

Molecular genetics and metabolism - 1 Apr 2011

Mendes Ana Isabel, Mascarenhas Mário Rui, Matos Sónia, Sousa Inês, Ferreira Joana, Barbosa Ana Paula, Bicho Manuel, Jordan Peter

Abstract excerpt

Germline mutations in the WNK4 gene originate Gordon syndrome or pseudohypoaldosteronism type II, a familial form of hypertension with hyperkalemia and hypercalciuria. In order to elucidate the contribution of WNK4 genetic variants to hypertension and/or osteoporosis, we analyzed 271 control indi...

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Source

Identifiers

PMID: 21236712
DOI: 10.1016/j.ymgme.2010.12.010

Genes

WNK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21236712-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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