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Article

Helicobacter pylori induces mitochondrial DNA mutation and reactive oxygen species level in AGS cells.

International journal of medical sciences - 8 Jan 2011

Huang Xue-Wen, Luo Rui-Hua, Zhao Qi, Shen Zhong-Ze, Huang Li-Li, An Xian-Yuan, Zhao Lan-Jing, Wang Jie, Huang Yu-Zheng

Abstract excerpt

To investigate the role of ROS in the helicobacter pylori (Hp) induced mtDNA mutations, AGS cells were treated by extracts of Hp11638 or Hp11638M. The ROS levels, cytochrome C reductions, and intracellular ATP levels were measured. The coding region and the D-Loop region were amplified and sequenced. Results showed the ROS levels, cytochrome C reduction and mtDNA mutations were markedly increased and cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21234270
DOI: 10.7150/ijms.8.56
PMCID: PMC3020393

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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