Article
Oxidative-stress resistance mutants of Helicobacter pylori.
Journal of bacteriology - 1 Jun 2002
Olczak Adriana A, Olson Jonathan W, Maier Robert J
Abstract excerpt
Within a large family of peroxidases, one member that catalyzes the reduction of organic peroxides to alcohols is known as alkyl hydroperoxide reductase, or AhpC. Gene disruption mutations in the gene encoding AhpC of Helicobacter pylori (ahpC) were generated by screening transformants under low-oxygen conditions. Two classes of mutants were obtained. Both types lack AhpC protein, but the major class (type I)...
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