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N ‐Acetylcysteine Reduces ROS‐Mediated Oxidative DNA Damage and PI3K/Akt Pathway Activation Induced by Helicobacter pylori Infection

1 Jan 2018

Abstract excerpt

Background . H. pylori infection induces reactive oxygen species‐ (ROS‐) related DNA damage and activates the PI3K/Akt pathway in gastric epithelial cells. N ‐Acetylcysteine (NAC) is known as an inhibitor of ROS; the role of NAC in H. pylori ‐related diseases is unclear. Aim . The aim of this study was to evaluate the role of ROS and the protective role of NAC in the pathogenesis of H. pylori ‐related diseases....

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Identifiers

PMID: 29854076
DOI: 10.1155/2018/1874985

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