Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cannabis use and age at onset of psychosis: further evidence of interaction with COMT Val158Met polymorphism.

Acta psychiatrica Scandinavica - 1 Jun 2011

Estrada G, Fatjó-Vilas M, Muñoz M J, Pulido G, Miñano M J, Toledo E, Illa J M, Martín M, Miralles M L, Miret S, Campanera S, Bernabeu C, Navarro M E, Fañanás L

Abstract excerpt

OBJECTIVE: To examine, in a sample of young psychiatric patients, (n = 157, mean age 17.01 years (SD = 3.6)) whether i) age at first cannabis use and age at emergence of psychiatric disorders are related and ii) such a relationship is modulated by the Val158Met polymorphism in the COMT gene. METH...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Catechol O-Methyltransferase
Share to Marijuana Abuse

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Methionine

Share to Polymorphism, Genetic

Share to Psychotic Disorders

Share to Schizophrenia

Share to Valine

Source

Identifiers

PMID: 21231925
DOI: 10.1111/j.1600-0447.2010.01665.x

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21231925-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cannabis use and age at onset of psychosis: further evidence of interaction with COMT Val158Met polymorphism.PMID 21231925Read ↗

Cannabis use, COMT, BDNF and age at first-episode psychosis.Semantic proximity Read ↗

Investigation of the COMT Val158Met variant association with age of onset of psychosis, adjusting for cannabis use.Semantic proximity Read ↗

Age at onset of psychotic disorder: Cannabis, BDNF Val66Met, and sex‐specific models of gene–environment interactionSemantic proximity Read ↗

Catechol-O-Methyltransferase (COMT) Val158Met variations and cannabis use in first-episode non-affective psychosis: clinical-onset implications.Semantic proximity Read ↗

Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction.Semantic proximity Read ↗

COMT Val(158)Met genotype and cannabis use in people with an At Risk Mental State for psychosis: Exploring Gene x Environment interactions.Semantic proximity Read ↗

Cannabis use and psychosis: theme introduction.Semantic proximity Read ↗

Cannabis, COMT and psychotic experiences.Semantic proximity Read ↗

Genetic dissection of the psychotomimetic effects of cannabinoid exposure.Semantic proximity Read ↗

Genome-wide association meta-analysis of age at first cannabis use.Semantic proximity Read ↗

The effect of childhood maltreatment and cannabis use on adult psychotic symptoms is modified by the COMT Val¹⁵⁸Met polymorphism.Semantic proximity Read ↗

Adolescent cannabis use increases risk for cocaine-induced paranoia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.