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Article

Impact of CYP2C9 and VKORC1 genetic polymorphisms upon warfarin dose requirements in Egyptian patients with acute coronary syndrome.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jul 2015

Ghozlan Manal F, Foad Dina A, Darwish Yasser W, Saad Abeer A

Abstract excerpt

Warfarin is the most widely prescribed anticoagulant drugs. Cytochrome P450-2C9 (CYP2C9) and vitamin K epoxide reductase-oxidaxe complex subunit 1 (VKORC1) contribute significantly to the variability of warfarin dose requirements among patients. We investigated the impact of CYP2C9 and VKORC1 polymorphisms on the variability of warfarin dosage requirements in Egyptian patients with acute coronary syndrome and...

Read the complete abstract on PubMed

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Share to Acute Coronary Syndrome
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Vitamin K Epoxide Reductases

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Source

Identifiers

PMID: 25699611
DOI: 10.1097/MBC.0000000000000272

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Impact of CYP2C9 and VKORC1 genetic polymorphisms upon warfarin dose requirements in Egyptian patients with acute coronary syndrome.PMID 25699611Read ↗

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