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Article

Lipopolysaccharide-induced activation of NF-κB non-canonical pathway requires BCL10 serine 138 and NIK phosphorylations.

Experimental cell research - 15 Nov 2010

Bhattacharyya Sumit, Borthakur Alip, Dudeja Pradeep K, Tobacman Joanne K

Abstract excerpt

BACKGROUND AND AIMS: B-cell lymphoma/leukemia (BCL)-10 and reactive oxygen species mediate two pathways of NF-κB (RelA) activation by lipopolysaccharide (LPS) in human colonic epithelial cells. The pathway for LPS activation of RelB by the non-canonical pathway (RelB) in non-myeloid cells was not yet reported, but important for understanding the range of potential microbial LPS-induced effects in inflammatory...

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Identifiers

PMID: 20466000
DOI: 10.1016/j.yexcr.2010.05.004
PMCID: PMC2963716

Genes

BCL10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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