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Article

Progressive multifocal leukoencephalopathy in a patient with novel mutation in the RAC2 gene: a case report.

Journal of medical case reports - 11 Jun 2022

Bahrami Sima, Arshi Saba, Nabavi Mohammad, Bemanian Mohammad Hassan, Fallahpour Morteza, Rezaeifar Afshin, Shokri Sima

Abstract excerpt

BACKGROUND: Progressive multifocal leukoencephalopathy is a rare demyelinating disease that is often secondary to lytic destruction of oligodendrocytes and, to a lesser extent, to astrocytes' response to human neurotrophic John Cunningham polyomavirus. Any underlying congenital disorder of primary or secondary immunodeficiency may predispose to virus infection and possible invasion of the brain. We present the...

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Identifiers

PMID: 35689244
DOI: 10.1186/s13256-022-03333-7
PMCID: PMC9188039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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