Article
Stargazin and AMPA receptor membrane expression is increased in the somatosensory cortex of Genetic Absence Epilepsy Rats from Strasbourg.
Neurobiology of disease - 1 Apr 2011
Kennard J T T, Barmanray R, Sampurno S, Ozturk E, Reid C A, Paradiso L, D'Abaco G M, Kaye A H, Foote S J, O'Brien T J, Powell K L
Abstract excerpt
Absence-like seizures in the Genetic Absence Epilepsy Rats from Strasbourg (GAERS) model are believed to arise in hyperexcitable somatosensory cortical neurons, however the cellular basis of this increased excitability remains unknown. We have previously shown that expression of the Transmembrane AMPA receptor Regulatory Protein (TARP), stargazin, is elevated in the somatosensory cortex of GAERS. TARPs are...
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