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Article

Association of TIRAP (MAL) gene polymorhisms with susceptibility to tuberculosis in a Chinese population.

Genetics and molecular research : GMR - 4 Jan 2011

Zhang Y X, Xue Y, Liu J Y, Zhao M Y, Li F J, Zhou J M, Wang H J, Li J C

Abstract excerpt

Toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP; also known as MAL) is an essential adaptor molecule in Toll-like receptor signaling, involved in activating the innate immune response during infection. Genetic variations in the TIRAP gene may influence human susceptibility to infectious disease. To date, in the Chinese population, a possible predisposition of TIRAP gene variants to...

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Source

Identifiers

PMID: 21218381
DOI: 10.4238/vol10-1gmr980

Genes

TIRAP
MAL

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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