Article
TIRAP C539T polymorphism contributes to tuberculosis susceptibility: evidence from a meta-analysis.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2014
Liu Qianqian, Li Wenzhang, Li Dongdong, Feng Yulin, Tao Chuanmin
Abstract excerpt
BACKGROUND: Toll-interleukin 1 receptor domain containing adaptor protein (TIRAP), an important adaptor protein downstream of the Toll-like receptor (TLR) 2 and 4 pathways, is highly involved in the activation and coordination of the anti-mycobacterial immune response. We performed a meta-analysis to assess the association between TIRAP C539T polymorphism and tuberculosis (TB) risk. METHODS: A systematic...
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