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Article

Meta-analysis on the association of TIRAP S180L variant and tuberculosis susceptibility.

Tuberculosis (Edinburgh, Scotland) - 1 May 2011

Miao Ruifen, Li Jiequan, Sun Zhaoping, Xu Fei, Shen Hongbing

Abstract excerpt

The missense variant S180L in TIRAP (Toll-interleukin-1 receptor domain-containing adaptor protein) gene is implicated in attenuating TLRs signal transaction and may affect individual response to Mycobacterium tuberculosis infection. Several studies investigated the association between TIRAP S180L and risk of tuberculosis (TB), but the results were controversial. In this study, we quantitatively synthesized nine...

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Source

Identifiers

PMID: 21419702
DOI: 10.1016/j.tube.2011.01.006

Genes

TIRAP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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