Article
Toll-like receptor and TIRAP gene polymorphisms in pulmonary tuberculosis patients of South India.
Tuberculosis (Edinburgh, Scotland) - 1 Sept 2010
Selvaraj P, Harishankar M, Singh Brijendra, Jawahar M S, Banurekha V V
Abstract excerpt
Toll-like receptors (TLRs) are pattern recognition receptors and play an important role in innate immunity. Changes in TLRs and signaling molecules that result from polymorphisms are often associated with susceptibility to various infectious diseases. In the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T...
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