Article
HLA-B*1502 genotyping in two Chinese patients with phenytoin-induced Stevens-Johnson syndrome.
Epilepsy & behavior : E&B - 1 Feb 2011
Min Fu-Li, Shi Yi-Wu, Liu Xiao-Rong, Liao Wei-Ping
Abstract excerpt
Previous studies have reported that patients with phenytoin-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (PHT-induced SJS/TEN) were positive for HLA-B*1502. We genotyped two patients with PHT-induced SJS using both polymerase chain reaction with sequence-specific primers and sequencing. The results revealed that one patient from Henan Province had HLA-B*1501/B*5401, and the other patient from...
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