Article
Association between HLA and Stevens-Johnson syndrome induced by carbamazepine in Southern Han Chinese: genetic markers besides B*1502?
Basic & clinical pharmacology & toxicology - 1 Jul 2012
Shi Yi-Wu, Min Fu-Li, Qin Bin, Zou Xin, Liu Xiao-Rong, Gao Mei-Mei, Wang Qian, Zhou Jue-Qian, Liao Wei-Ping
Abstract excerpt
Previous studies have demonstrated a strong association between carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (CBZ-induced SJS/TEN) and HLA-B*1502 in Chinese, and HLA-A*3101 but not HLA-B*1502 in Caucasians and Japanese. Cases with CBZ-induced SJS/TEN negative for HLA-B*1502 were reported recently in Southeast Asia. Negative correlations between CBZ-induced SJS/TEN and B*0702 or...
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