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Article

Association of HLA-B*1502 allele with lamotrigine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese subjects: a meta-analysis.

International journal of dermatology - 1 Apr 2015

Zeng Tao, Long Yue-Sheng, Min Fu-Li, Liao Wei-Ping, Shi Yi-Wu

Abstract excerpt

BACKGROUND: Despite several studies investigating the association between the human leukocyte antigen HLA-B*1502 allele and lamotrigine-induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in Han Chinese subjects, the relationship remains unclear. OBJECTIVES: We performed a systematic review and meta-analysis to ascertain the association between the HLA-B*1502 allele and lamotrigine-induced...

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PMID: 25428396
DOI: 10.1111/ijd.12570

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