Article
Association between HLA-B*1502 allele and carbamazepine-induced severe cutaneous adverse reactions in Han people of southern China mainland.
Seizure - 1 Jul 2011
Wang Qian, Zhou Jue-qian, Zhou Lie-min, Chen Zi-yi, Fang Zi-yan, Chen Shu-da, Yang Li-bai, Cai Xiao-dong, Dai Qi-lin, Hong Hua, Wang Hong-xuan
Abstract excerpt
Previous studies have found a strong association between HLA-B*1502 and carbamazepine-induced Stevens-Johnson syndrome in Asian areas including Taiwan, Hongkong and Thailand. This study explores the association between HLA-B*1502 allele and carbamazepine-induced cutaneous adverse reactions in Han Chinese of southern China mainland, and find the genetic marker that can predict carbamazepine-induced cutaneous...
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